Does ivabradine cause hypertension?

Does ivabradine cause hypertension?

The most common adverse effects include bradycardia, atrial fibrillation, high blood pressure, and phosphenes. Ivabradine can cause bradycardia, sinus arrest, and heart block.

What drug group is ivabradine?

Ivabradine is in a class of medications called hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers. It works by slowing the heart rate so the heart can pump more blood through the body each time it beats.

When should I stop taking ivabradine?

If your heart rate is less than 50 beats a minute, your healthcare provider might lower the dose or ask you to stop taking it.

Does ivabradine help anxiety?

We conclude that ivabradine showed no undesirable effects on anxiety, locomotion or learning; in fact, some of these parameters were even improved. For the first time it has been shown that ivabradine is a safe cardiovascular drug regarding its effect on psycho-behavioral manifestations.

Who should not take ivabradine?

You should not use ivabradine if you have severe liver disease, very low blood pressure, a slow resting heart rate, a serious heart condition such as “sick sinus syndrome” or 3rd-degree “AV block” (unless you have a pacemaker), or if you depend on a pacemaker to control your heart rate.

Does ivabradine lower blood pressure?

Systolic BP was reduced from the first week by ivabradine treatment and continued to decrease each week. In the fourth week of the experiment, ivabradine reduced systolic BP by 15%, and the 4 week average systolic BP was decreased by 8% via ivabradine compared to that in the L-NAME group (19).

Can I exercise while taking ivabradine?

The novel rate-lowering drug ivabradine results in a dose-dependent HR reduction at rest and during exercise.

Can ivabradine cause palpitations?

Less commonly Ivabradine can cause palpitations and extra heart beats, feeling sick (nausea), constipation, diarrhoea, spinning sensation (vertigo), difficulty breathing (dyspnoea), muscle cramps.