What is hyaluronidase quizlet?

What is hyaluronidase quizlet?

Hyaluronidase. is the ORIGINAL SPREADING FACTOR. It is produced by streptococci. staphylococci, and clostridia. The enzyme attacks the interstitial cement (“ground substance”) of connective tissue by depolymerizing hyaluronic acid.

How does the virulence factor hyaluronidase benefit a pathogen?

Hyaluronidase in snake and insect venom is thought to function as a “spreading factor” by degrading host hyaluronic acid, thus allowing spread of toxin (13). Another gram-positive bacterium, Clostridium perfringens produces hyaluronidases that are also thought to contribute to the spreading of bacteria in tissues (2).

Which of the following virulence factors would be found in Staphylococcus aureus?

It is well known that S. aureus produces many virulence factors, such as hemolysins, leukocidins, proteases, enterotoxins, exfoliative toxins, and immune-modulatory factors (11, 12, 21, 31). The expression of these factors is tightly regulated during growth.

What are bacterial enzymes that dissolve fibrin clots?

T.P.A. is one link in a complex chain reaction within the bloodstream. It is produced naturally to convert another blood protein, known as plasminogen, into an enzyme called plasmin. This, in turn, dissolves fibrin, the material that holds clots together.

What substance is called the spreading factor?

1. Hyaluronidase – This is also called the spreading factor because it catalyzes the breakdown of hyaluronic acid, the. substance that cements the human cells together. This allows the bacterial cells to spread through tissue causing a. condition known as cellulitis.

What is hyaluronidase in?

(HY-al-yoo-RAH-nih-days) An enzyme that breaks down a substance in the body called hyaluronic acid. Hyaluronic acid is found throughout the body in connective tissue, skin, and fluids in the joints and inside the eye.

What is the meaning of hyaluronidase?

Definition of hyaluronidase : a mucolytic enzyme that facilitates the spread of fluids through tissues by lowering the viscosity of hyaluronic acid.

What do hyaluronidase and kinase have in common quizlet?

What do hyaluronidase and kinase have in common? They are both enzymes involved in evading host defense. They are able to detect structures on the surfaces of foreign cells that are not found in the host.

What substance dissolves clots?

Tissue plasminogen activator (tPA) is currently the most expensive drug for dissolving blood clots. It is unique because it activates only fibrin-bound plasminogen and thus targets the clot site. tPA in human blood is produced in very small amounts by vascular endothelial cells.