What is the most common cause of thrombocytopenia in pregnancy?

What is the most common cause of thrombocytopenia in pregnancy?

Gestational thrombocytopenia (defined as a mild thrombocytopenia, occurring during the 3 rd trimester with spontaneous resolution postpartum and no neonatal thrombocytopenia) is the most common cause of thrombocytopenia during pregnancy but a low platelet can also be associated with several diseases, either pregnancy …

What causes thrombocytopenia in pregnancy?

Platelets may be destroyed at a higher rate in pregnancy. As the spleen increases in size due to increased blood volume during pregnancy, it may destroy more platelets in the filtering process. A severe lack of folic acid in your blood can cause thrombocytopenia, so it is important to take your prenatal vitamins.

Why does thrombocytopenia happen in preeclampsia?

The most severe spectrum of preeclampsia is established when the vascular endothelial damage produces microangiopathic hemolytic anemia, elevating liver enzymes along with thrombocytopenia and establishing a syndrome known as HELLP (hemolysis, elevated liver enzymes, low platelets).

Why does Hellp cause low platelets?

Platelets release thromboxane A and serotonin, causing vasospasm, platelet aggregation, and further endothelial damage. The cascade only terminates with the delivery of the fetus. This causes the usage of platelets and hence, thrombocytopenia.

How do I treat thrombocytopenia in pregnancy?

Medications. Glucocorticoids may be taken intravenously or by mouth.

  • Platelet transfusions. Transfusions of platelets usually are reserved for patients with active bleeding or a high risk of bleeding.
  • Splenectomy (surgical removal of the spleen). This may be necessary if ITP that has not improved with other treatment.
  • What causes high platelet count in pregnancy?

    High blood platelets in pregnancy. High blood platelets in pregnancy are rather uncommon as it is usually a low platelet count which is there in pregnant mothers. However, if the count is high it could be because of an essential requirement wherein the bone marrow is producing excess or platelets or an inflammation in the system which is causing it.

    What is the range of thrombocytopenia in pregnancy?

    Gestational (incidental) thrombocytopenia is a condition that commonly affects pregnant women. Thrombocytopenia is defined as the drop in platelet count from the normal range of 150,000 -400,000 / μL to a count lower than 150,000 / μL.

    What causes high platelets during pregnancy?

    However, an abnormally high number of platelets in pregnancy is far less common than low platelet levels, and the causes could range from infection, medication, disease or inflammation. In certain cases, increased platelet count can give rise to serious complications as a result of unexplained blood clotting.