What gender does XYY syndrome affect?
XYY syndrome is a rare chromosomal disorder present at birth that affects only males.
What are the symptoms of 47 XYY syndrome?
Boys with XYY syndrome — also known as 47,XYY — might be taller than other boys. Other symptoms can include problems with spoken language and processing spoken words, coordination problems, weaker muscles, hand tremors, and behavioral problems.
How common is 47 XYY?
This condition occurs in about 1 in 1,000 newborn boys. Five to 10 boys with 47,XYY syndrome are born in the United States each day. Many affected males are never diagnosed or not diagnosed until later in life.
How common is 47 Xyy?
What is the cause of 47, XYY syndrome?
47,XYY syndrome is caused by the presence of an extra copy of the Y chromosome in each of a male’s cells. As a result of the extra Y chromosome, each cell has a total of 47 chromosomes instead of the usual 46.
What are the signs and symptoms of XYY syndrome?
For some males with this syndrome, signs and symptoms are barely noticeable. For others, signs and symptoms may include learning disabilities, speech delay, low muscle tone (hypotonia), and being taller than expected.
What to do for men with 47, XYY syndrome?
Fertility Management. However, for those men with 47,XXY syndrome who have difficulty achieving pregnancy, in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) is likely going to be required to achieve pregnancy due to the high prevalence of oligospermia as well as abnormal sperm chromosomal constitution.
How is XYY syndrome related to male infertility?
Fertility Effects. Some researchers have suggested that the extra Y chromosome is lost before meiosis, 3,6–8 thus conserving fertility in these patients. Studies comparing sperm aneuploidy between fertile and infertile XYY men reveal that most sperm produced by XYY men have a normal karyotype.