How is triphenylmethanol formed?
Formation of triphenylmethanol In an oven dried vial, dissolve benzophenone (364 mg, 2 mmol) in 1 mL of anhydrous ether. With a dry 1 mL syringe, slowly add the solution to the reaction vessel containing the Grignard reagent, thus maintaining a gentle reflux.
What is Triphenylmethanol used for?
Triphenylmethanol is used as a reagent in the research laboratory. It acts as an intermediate in the production of the commercially useful triarylmethane dyes. It is used in the preparation of triphenylmethane. It is also used as an antiproliferative agent.
Why is Triphenylmethanol important?
What is the density of triphenylmethanol?
1.2 g/cm³
Triphenylmethanol/Density
Why is Grignard reagent used?
Grignard reagent can be used for determining the number of halogen atoms present in a halogen compound. Currently, Grignard degradation is used for the chemical analysis of certain triacylglycerols. Industrially, the Grignard reaction is the key step in the production of Tamoxifen , which is used in the treatment of breast cancer.
Does Grignard reagent react with oxygen?
Grignard reagents commonly are prepared by reaction of an organohalogen with magnesium in a nitrogen atmosphere because the reagent is very reactive toward oxygen and moisture.
Why is the Grignard reaction important?
The Grignard reaction (pronounced /ɡriɲar/) is an organometallic chemical reaction in which alkyl, vinyl, or aryl-magnesium halides (Grignard reagent) add to a carbonyl group in an aldehyde or ketone. This reaction is important for the formation of carbon–carbon bonds.
What is the limiting reagent in Grignard reaction?
The limiting reagent in a Grignard reaction is usually the substance to which you add the Grignard reagent, but you have to confirm this by calculation. Assume that, in a preparation of triphenylmethanol, you prepared phenylmagnesium bromide by reacting 2.1 mL of bromobenzene (density 1.50 g/mL) with 0.50 g of magnesium in anhydrous ether.