What is the drug of choice for chloroquine resistant malaria?
These results indicate that berberine is more effective in clearing the parasite than both tetracycline and cotrimoxazole, and that the combination of pyrimethamine and berberine gives the best results for chloroquine resistant malaria.
Is malaria resistant to quinine?
Over the years, malaria parasites have developed resistance to a number of commonly used anti-malarial drugs. However the development of resistance to quinine has been slow. Although its use started in the 17th century, resistance to quinine was first reported in 1910 [88].
Which of the following drugs can be used for the treatment of chloroquine-resistant malaria in children?
Artemisinin-based combination therapies (ACTs). This is usually the preferred treatment for chloroquine-resistant malaria. Examples include artemether-lumefantrine (Coartem) and artesunate-mefloquine.
Which is effective in treating chloroquine-resistant strains of Plasmodium?
Amodiaquine, a 4-aminoquinoline which has been shown to be effective in treating infections with chloroquine-resistant strains of Plasmodium falciparum, was evaluated against chloroquine-resistant infections in children in Zanzibar, Tanzania, during July 1982.
Is quinine an antiviral?
Quinine has antimicrobial activities useful for the treatment of bacteria and viruses. For instance, it has been shown in vitro that quinine has antiviral activity against dengue, herpes simplex, and influenza A viruses [53–55].
Which countries are chloroquine-resistant?
Drug-resistant P. P. vivax resistance to chloroquine has also now been identified in Southeast Asia, Ethiopia , and Madagascar. Isolated reports have suggested chloroquine-resistance P. vivax in other countries and regions, but further evaluation is needed.
How do you treat chloroquine-resistant falciparum?
Because the other drugs effective against chloroquine-resistant P falciparum may produce uterine stimulation (quinine sulfate) or damage the fetal skeleton (tetracyclines), the pyrimethamine-sulfonamide combination (with folinic acid supplementation) may be the best available choice for the treatment and prophylaxis of …