Does atropine cause fever?
When atropine is administered as anesthetic premedication, it suppresses the activity of sweat glands, which are innervated by sympathetic nerves that utilize the neurotransmitter acetylcholine, resulting in heat retention. This phenomenon often develops into a high fever known as ‘atropine fever’ [8, 9].
Why does atropine increase body temperature?
Microinjection of atropine directly into the hypothalamic thermoregulatory centers causes a rise in core temperature. The central hyperthermic effect of atropine may be due to blockade of endogenous cholinergic transmitters.
What drugs can produce hyperthermia?
Drugs that alter the neurotransmitters noradrenaline (norepinephrine), dopamine and serotonin can affect thermoregulation by the hypothalamic–pituitary– adrenal axis. In drug-induced hyperthermia the core temperature is at least 38.3 °C.
How is atropine absorbed?
Pharmacokinetics: Atropine is rapidly and well absorbed after intramuscular administration. Atropine disappears rapidly from the blood and is distributed throughout the various body tissues and fluids.
What are the side effect of atropine?
COMMON side effects
- visual sensitivity to light.
- blurred vision.
- dry eye.
- dry mouth.
- constipation.
- decreased sweating.
- reactions at the site of the injection.
- intense abdominal pain.
What drugs can cause low body temperature?
Hypothermia may be related to drug administration; such medications include beta-blockers, clonidine, meperidine, neuroleptics, and general anesthetic agents. Ethanol, phenothiazines, and sedative-hypnotics also reduce the body’s ability to respond to low ambient temperatures.
What temperature causes hyperthermia?
It refers to several conditions that can occur when your body’s heat-regulation system can’t handle the heat in your environment. You’re said to have severe hyperthermia if your body temperature is above 104°F (40°C). By comparison, a body temperature of 95°F (35°C) or lower is considered hypothermic.
Are there any side effects with atropine for dogs?
Precautions and Side Effects 1 While generally safe and effective when prescribed by a veterinarian, atropine can cause side effects in some animals. 2 Atropine should not be used in animals with known hypersensitivity or allergy to the drug. 3 It should also not be used if a gastrointestinal obstruction or infection is suspected.
What does atropine do to the nervous system?
Atropine is administered to block the effect of certain nervous system impulses (acetylcholine) on receptors throughout the body.
What can cause malignant hyperthermia in a dog?
Malignant hyperthermia is triggered in susceptible animals by excitement, apprehension, exercise, or environmental stress. Giving certain anesthetics or specific drugs that affect the neurologic and muscular systems also consistently triggers malignant hyperthermia in susceptible animals.
Can a sedation drug cause hyperthermia in a dog?
Rarely, certain veterinary anesthetic drugs can cause malignant hyperthermia in dogs. While this is very rare, it’s one of the reasons why we veterinarians so carefully monitor the body temperature after sedation or general anesthesia. Certain breeds such as greyhounds and Labrador retrievers may potentially be more at risk.