What is the yield of aspirin?
The percent yield of the aspirin obtained from the experiment is 46.3% yield. The higher the yield percentage, the higher the purity of the aspirin will be.
What can be the reason for 100% yield in aspirin synthesis experiment?
Using the theoretical and actual you can calculate percent yield. Your value may vary from the theoretical value for a number of reasons. If it is above 100%, it may be because your aspirin was not completely dried. If it is below 100%, it may be because of sample loss when transferring to the weigh paper.
What affects the yield of aspirin?
Weighing, mixing, heating, cooling, filtration, washing and drying are processes that can affect the yield and the purity of aspirin. In the chemical reaction, most of the time the aspirin produced might be impure. Therefore, aspirin must go through another process known as recrystallization.
How can you increase the yield of aspirin synthesis?
In a reflux reaction with aspirin, the best yield should be obtained by heating the mixture of reactants around above the solvents boiling point. This will allow for optimal heat and higher rate of collisions during reaction, allowing more product to be produced.
What is the theoretical yield of aspirin if you started your synthesis with 5.6 g of salicylic acid?
1 Expert Answer This is 2.633 g of aspirin (the theoretical yield).
What are two possible reasons why your yield is different from 100%?
Usually, percent yield is lower than 100% because the actual yield is often less than the theoretical value. Reasons for this can include incomplete or competing reactions and loss of sample during recovery.
What is the theoretical yield of aspirin in your synthesis?
2.520 grams
Thus, the calculated value of crude synthesized aspirin was 3.029 grams. Following purification, the calculated mass of the final aspirin product was 2.169 grams. The calculated theoretical yield was 2.520 grams.
How do you increase recrystallization yield?
The yield could have been improved by repeating the recrystallization process in order for the substance to be at its purest form. Also, increasing the time of the solution cooling to room temperature so it can form larger crystals then putting it in the ice bath would yield more crystals.
How does recrystallization affect purity of aspirin?
The process of recrystallisation in my experiment increased the purity of Aspirin but with a decrease in the quantity produced.
How do you increase yield of recrystallization?
Tips for maximizing yield, purity and crystal size during…
- allow the solution cool down as slowly as possible.
- maintain a low relative supersaturation of the solution, this will increase crystal size and improve purity.
What is the pKa of aspirin?
3.5
A number of commonly used drugs are carboxylic acid derivatives. These include aspirin (pKa 3.5), the anticancer compound methotrexate (pKa 3.8, 4.8 and 5.6) and the diuretic (previously called frusemide in the UK; pKa 3.9).