Is tocilizumab subcutaneous?
Subcutaneous tocilizumab (TCZ-SC) is a desirable alternative to existing subcutaneous biological disease modifying antirheumatic drugs (bDMARDs) targeting tumor necrosis factor. TCZ-SC efficacy has been evaluated in three randomized controlled trials.
How is ACTEMRA dispensed?
ACTEMRA can be taken in different ways for polyarticular juvenile idiopathic arthritis (PJIA) symptoms. Intravenous (IV) infusion: This medicine is a liquid solution placed into a vein with a needle. It is given at a doctor’s office or an infusion center every 4 weeks.
Is ACTEMRA self administered?
When injecting ACTEMRA subcutaneous (SC), pediatric patients may self-inject if both the healthcare provider and caregiver find it appropriate. Caregivers may inject pediatric patients with either the prefilled syringe or the ACTPen.
Can ACTEMRA be self administered?
How do you administer IV tocilizumab?
Tocilizumab is administered as an IV infusion at a dose of 8 mg/kg every 4 weeks. The dose is diluted in 100 ml sodium chloride 0.9% and administered over 1 hour. If actual body weight (ABW) is >100kg then the maximum recommended dose is 800mg.
How do you infuse tocilizumab?
Tocilizumab is administered as an IV infusion at a dose of 8 mg/kg every 4 weeks. The dose is diluted in 100 ml sodium chloride 0.9% and administered over 1 hour.
How much Actemra is in a syringe for subcutaneous use?
Patients using ACTEMRA for subcutaneous administration should be instructed to inject the full amount in the syringe (0.9 ml) or full amount in the ACTPen autoinjector (0.9 ml), which provide 162 mg of ACTEMRA, according to the directions provided in the Instructions for Use.
How often should I take Actemra for GCA?
Recommended Adult Subcutaneous (SC) Dosage: The recommended dose of ACTEMRA for adult patients with GCA is 162 mg given once every week as a subcutaneous injection, in combination with a tapering course of glucocorticoids.
When to take Actemra tocilizumab in adults?
ACTEMRA® (tocilizumab) is indicated for the treatment of chimeric antigen receptor (CAR) T cell-induced severe or life-threatening cytokine release syndrome in adults and pediatric patients 2 years of age and older.
What kind of rheumatoid arthritis does Actemra treat?
ACTEMRA is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs). ACTEMRA is indicated for the treatment of giant cell arteritis (GCA) in adult patients.