What is tetrabenazine given for?
Tetrabenazine is used to treat chorea (sudden movements that you cannot control) caused by Huntington’s disease (an inherited disease that causes the progressive breakdown of nerve cells in the brain). Tetrabenazine is in a class of medications called vesicular monoamine transporter 2 (VMAT2) inhibitors.
What is Tetrazine medication?
Tartrazine is an azo dye, also known as FD&C Yellow No. 5 and is commonly used as a pharmaceutical colorant. It has been FDA-approved as a drug colorant for internal consumption, external use and around the eye area. In addition to use in pharmaceuticals as a dye, tartrazine is used as a food and cosmetic colorant.
What is the drug Austedo used for?
AUSTEDO is a prescription medicine that is used to treat: the involuntary movements (chorea) of Huntington’s disease. AUSTEDO does not cure the cause of the involuntary movements, and it does not treat other symptoms of Huntington’s disease, such as problems with thinking or emotions.
Is tetrabenazine an antipsychotic?
Tetrabenazine (TBZ) was initially synthesized in the 1950s by O Schneider and A Brossi at the research laboratory of Hoffmann-La Roche in Basel. They created TBZ as an antipsychotic drug as part of their research into simpler chemical compounds with reserpine-like activity.
Can tetrabenazine cause insomnia?
The most common side effects included drowsiness (36.5%), parkinsonism (28.5%), depression (15.0%), insomnia (11.0%), nervousness or anxiety (10.3%), and akathisia (9.5%). The side effects were controlled with reduction in the dosage.
What are the side effects of the drug AUSTEDO?
The most common side effects of AUSTEDO in people with Huntington’s disease include sleepiness (sedation), diarrhea, tiredness, and dry mouth. The most common side effects of AUSTEDO in people with tardive dyskinesia include inflammation of the nose and throat (nasopharyngitis) and problems sleeping (insomnia).
What does tetrabenazine do to dopamine?
Nervous system. Tetrabenazine inhibits vesicular monoamine transporter 2, leading to depletion of dopamine and other monoamines in the central nervous system.