What is the purpose of Grignard synthesis of triphenylmethanol?
Triphenylmethanol was synthesized with a 9.21 % yield. The purpose of the experiment is to synthesize triphenylmethanol from bromobenzene and benzophenone. When magnesium is added to the bromobenzene in ether, a Grignard reagent is formed.
Why is triphenylmethanol important?
Triphenylmethanol is used as a reagent in the research laboratory. It acts as an intermediate in the production of the commercially useful triarylmethane dyes. It is used in the preparation of triphenylmethane. It is also used as an antiproliferative agent.
Why must a Grignard reaction be kept dry?
After reaction, the desired product (an alcohol, as shown here) is formed after acidic hydrolysis. You must keep your reaction apparatus and reagents completely dry because water functions as an acid, and would cleave the Grignard reagent producing benzene. All glassware must be thoroughly clean and dry.
What is the theoretical yield of the product triphenylmethanol?
The product triphenylmethanol will then be purified by recrystallization, and percent- age yield is used to measure the success of reaction, in which a 29.08% yield was obtained.
What is Triphenylcarbinol used for?
What functional groups are in Triphenylmethanol?
Structure and properties Triphenylmethanol contains three phenyl rings and an alcohol group bound to a central tetrahedral carbon atom. All three C–Ph bonds are typical of sp3-sp2 carbon-carbon bonds with lengths of approximately 1.47 Å, while the C–O bond length is approximately 1.42 Å.
How is Grignard reagent used to prepare triphenylmethanol?
In anhydrous reaction conditions, the formation of Grignard reagents can occur when the reagent is reacted with an organic halide. As demonstrated in the lab, phenylmagnesium bromide, an organic halide, can react with methyl benzoate along with the Grignard reagent to produce triphenylmethanol.
What is the number of moles of triphenylmethanol?
Since the Grignard reagent is excess, the product is limited by methyl benzoate so that it is limiting reagent in the reaction. Thus, the number of mole of triphenylmethanol = 0.0255 mol. The purpose of this experiment is to synthesis triphenylmethanol by using Grignard reagent.
What kind of reagents are used in the Grignard reaction?
The Grignard reaction is a useful synthetic procedure for forming new carbon- carbon bonds. This organometallic chemical reaction involves alkyl- or aryl-magnesium halides, known as Grignard reagents.1 Grignard reagents are formed via the action of an alkyl or aryl halide on magnesium metal. 2
How is triphenylmethanol prepared from benzophenone?
Triphenylmethanol is prepared from benzophenone using a Grignard reagent e.g. phenyl magnesium bromide through nucleophilic acyl addition mechanism. “Magnesium alkoxide is formed as an intermediate, which is then hydrolyzed by HCL to give an ether soluble triphenylmethanol and a water-soluble salt of MgBrCl” (Addison 446).