Where is KPC usually found?

Where is KPC usually found?

Klebsiella bacteria are normally found in the human intestines (where they do not cause disease). They are also found in human stool (feces). In healthcare settings, Klebsiella infections commonly occur among sick patients who are receiving treatment for other conditions.

How many states have reported having KPC?

To date, KPC-producing bacteria have been isolated in at least 33 states.

Is KPC a superbug?

A 43-year-old woman with complications from a lung transplant is transferred from a New York City hospital with a highly resistant superbug known as KPC.

What antibiotics treat Klebsiella UTI?

K pneumoniae UTI Complicated cases may be treated with oral quinolones or with intravenous aminoglycosides, imipenem, aztreonam, third-generation cephalosporins, or piperacillin/tazobactam. Duration of treatment is usually 14-21 days. Intravenous agents are used until the fever resolves.

Which hospital had an outbreak of KPC?

the NIH Clinical Center
In 2011, deadly, drug-resistant Klebsiella pneumoniae carbapenemase (KPC) spread through the NIH Clinical Center in Bethesda, Md., puzzling health experts and leaving 11 patients dead.

What countries have a problem with resistant bacteria?

We find that China has the highest level of antibiotic resistance, followed by Kuwait and the U.S. In a study of resistance patterns of several most common bacteria in China in 1999 and 2001, the mean prevalence of resistance among hospital-acquired infections was as high as 41% (with a range from 23% to 77%) and that …

Where do many gram negative bacteria live in the body?

Gram-negative bacteria can be found most abundantly in the human body in the gastrointestinal tract, he says, which is where salmonella, shigella, e. coli and proteus organelli reside.

Where was the kpc 2 outbreak in Brazil?

The aim of this study was to describe the clinical and microbiologic aspects of KPC-producing K. pneumoniae infections in SOT recipients. A KPC-2-producing K. pneumoniae outbreak was identified in a public teaching tertiary care hospital in São Paulo, Brazil, in June 2009.

How many people died in the KPC outbreak?

Five other patients die, but the hospital believes their deaths are due to their underlying health problems, not the KPC infection. Ultimately, 11 infected patients die. Finally, the outbreak seems to have been contained. Throughout the outbreak, the hospital used genetic analysis to help understand the transmission sequence.

Who is at risk for infection with KPC?

Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae is spreading globally and represents a challenge in infection control and treatment. Solid organ transplant (SOT) recipients are especially at risk for infection by multidrug-resistant bacteria, and little is known about infection with KPC-producing organisms in this setting.

Where does Klebsiella pneumoniae carbapenemase ( KPC )-producing bacteria?

Abstract. Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria are a group of emerging highly drug-resistant Gram-negative bacilli causing infections associated with significant morbidity and mortality. Once confined to outbreaks in the northeastern United States (US), they have spread throughout the US and most of the world.

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