What is the molecular shape of aspirin?
The structure of aspirin is: For C1 to C3 and C6: The part of aspirin depicted in these carbon atoms is: The central carbon has 3 electron groups and no lone pairs, which means it’s molecular geometry is trigonal planar.
What chemicals are used to make aspirin?
To prepare aspirin, salicylic acid is reacted with an excess of acetic anhydride. A small amount of a strong acid is used as a catalyst which speeds up the reaction. In this experiment, phosphoric acid will be used as the catalyst. The excess acetic acid will be quenched with the addition of water.
How is aspirin metabolised?
Let’s look at aspirin as example of a drug being metabolised. Aspirin undergoes phase 1 hydrolysis to salicylic acid. In phase 2 it is congugated with either glycine or glucoronic acid forming a range of ionised metabolytes that can then be excreted in the urine.
What is the Iupac name of aspirin?
2-Acetoxybenzoic acid
Aspirin/IUPAC ID
Is aspirin hygroscopic?
Aspirin is hygroscopic and is rapidly hydrolysed to salicylic acid (SA) on exposure to moisture (according to the British Pharma- copoeia (BP), the limit of the SA content within a dispersible aspirin tablets is 3%).
Is aspirin polar or nonpolar?
Aspirin is a polar molecule with dipole-dipole attraction bonds and an -OH (hydroxyl) segment as part of a carboxylic acid group.
How do we manufacture aspirin?
Aspirin is prepared by chemical synthesis from salicylic acid, through acetylation with acetic anhydride. The molecular weight of aspirin is 180.16g/mol. It is odourless, colourless to white crystals or crystalline powder.
Is aspirin metabolised in liver?
Salicylate is mainly metabolized in the liver, although other tissues may also be involved in this process Label. The major metabolites of acetylsalicylic acid are salicylic acid, salicyluric acid, the ether or phenolic glucuronide and the ester or acyl glucuronide.
How is aspirin Synthesised?
What is the molecular weight of an aspirin?
By looking at its chemical structure, you’ll see that it’s composed of three different types of atoms: carbon, hydrogen, and oxygen. These atoms are either single or double bonded together to form the overall structure of aspirin. The molecular formula of aspirin is C 9 H 8 O 4. Its molecular weight is 180.157 grams/mole.
Where are the carbon atoms located in aspirin?
The carbon atoms in the chemical structure of aspirin are implied to be located at the corner (s) and hydrogen atoms attached to carbon atoms are not indicated – each carbon atom is considered to be associated with enough hydrogen atoms to provide the carbon atom with four bonds.
What are the three functional groups in aspirin?
It has the molecular formula C 9 H 8 O 4 and a molecular weight of 180.157g/mol. There are three different functional groups in aspirin, which contribute to its properties, a weak acid soluble in basic solutions. These functional groups include carboxylic acid, ester, and an aromatic group.
What is the chemical formula for aspirin Pubchem CID 2244?
Aspirin PubChem CID 2244 Structure Find Similar Structures Chemical Safety Laboratory Chemical Safety Summary (LCSS Molecular Formula C9H8O4 or CH3COOC6H4COOH or HC9H7O4 Synonyms aspirin ACETYLSALICYLIC ACID 50-78-2